![]() ![]() Cefquinome exhibited time-dependent killing and produced in vitro PAEs increasing with concentration and time of exposure. In vitro post antibiotic effects (PAEs) and mutant prevention concentrations were determined with S. Cefquinome kinetics were measured by liquid chromatography and UV detection. The aim of our study was to observe the ex-vivo activity of cefquinome against Staphylococcus aureus strains by using bovine serum from intravenously treated cattle. 4Laboratory of Fougères, French Agency for Food, Environmental and Occupational Safety, Maisons-Alfort, FranceĬefquinome is a fourth generation cephalosporin with antimicrobial activity against gram negative and gram positive bacterial species, including Staphylococcus aureus.3Hubei Collaborative Innovation Centre for feed Safety and Animal Nutrition, Huazhong Agricultural University, Wuhan, China.2MOA Laboratory for Risk Assessment of Safety and Quality of Livestock and Poultry Products, Huazhong Agriculture University, Wuhan, China. ![]() 1National Reference Laboratory of Veterinary Drug Residues and MAO Key Laboratory for Drug Residues Detection, Huazhong Agriculture University, Wuhan, China.Ijaz Ahmad 1, Haihong Hao 2, Lingli Huang 2,3, Pascal Sanders 4, Xu Wang 2, Dongmei Chen 1,3, Yanfei Tao 1,3, Shuyu Xie 2,3, Kuang Xiuhua 2, Juan Li 2, Wan Dan 2 and Zonghui Yuan 1,2,3 *
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